A New Tinnitus Relief Brings New Hope For Sufferers: A Study
A new therapy called Vagus Nerve Stimulation-tone (VNS) is considered safe and brought significant improvement to some of tinnitus sufferers in a small clinical trial, according to UT Dallas researchers.Dr. Sven Vanneste and Michael Kilgard of the School of Behavioral and Brain Sciences used a new method pairing Vagus Nerve Stimulation with auditory tones to alleviate the symptoms of chronic tinnitus. As quoted from http://www.utdallas.edu, the results of their study were published on Nov. 20 in the journal Neuromodulation: Technology at the Neural Interface.
Vagus Nerve Stimulation is a method approved by FDA for treating various illnesses including depression and epilepsy. This method involves sending a mild electric pulse through the vagus nerve. It relays information about the state of the body to the brain.
Vanneste explained that the primary goal of the study was to evaluate safety of VNS-tone therapy in tinnitus sufferers. “ Vagus Nerve Stimulation-tone therapy was expected to be safe because it requires less than 1 percent of the VNS approved by the FDA for the treatment of intractable epilepsy and depression. Well, there were no significant adverse events in our study.” He added.
Estimates vary, but Vanneste said that more than 12 million Americans have tinnitus severe enough to seek medical attention. Unfortunately, of which 2 million are so disabled that they cannot function normally. In addition to that, he said that there has been no consistently effective treatment.
![]() |
A stimulation electrode was implanted directly on the vagus nerve of 10 tinnitus patients. They received 2 ½ hours of daily treatment for 20 days. Image source: utdallas.edu. |
Vagus Nerve Stimulation-tone For Tinnitus Relief
The study involved implanting 10 tinnitus sufferers with a stimulation electrode directly on the vagus nerve. The participants received 2 ½ hours of daily treatment for 20 days. They had lived with tinnitus for at least a year prior to participating in the study, and showed no benefit from previous audiological, medication, or neuromodulation therapy.
Electrical pulses were generated from an external device for this study; however, future work could involve using internal generators so that eliminating the need for clinical visits.
Results of The Study
Half of the participants demonstrated large decreases in their tinnitus symptoms in which three of them showing a 44-percent reduction in the impact of tinnitus on their daily lives. And four people demonstrated clinically meaningful reductions in the perceived loudness of their tinnitus by 26 decibels.
There were five participants on medications for other problems who did not show significant changes whereas other four participants who benefited from the therapy were not using any medications. This report attributes drug interactions as blocking the effects of the VNS-tone therapy.
Vanneste explained that in all four of the 10 patients showed relevant decreases on tinnitus questionnaires and audiological measures. “The observation that these improvements were stable for more than two months after the end of the one month therapy is encouraging.” He said.
Other researchers at the University Hospital Antwerp, Belgium, and MicroTransponder Inc. also contributed to the study.
For further study, a larger one involving four different centers will soon begin in the United States.






